skip to main content
Back to Top
Dr. DeFrance


Dr. Bryon De France is an Associate Professor in the Department of Obstetrics and Gynecology at McMaster University and a member of the active staff in the clinical Department of Obstetrics and Gynecology at Hamilton Health Sciences Corporation in Hamilton Ontario.  He is also an Associate Member of the Department of Diagnostic Imaging at McMaster University.  In addition, Dr. De France is one of the two lead Maternal Fetal Medicine physicians leading the McMaster Diabetes in Pregnancy Program at McMaster University.

He received his MD at McMaster University and continued there to complete his residency in Obstetrics and Gynecology and was the first Fellow in the Maternal Fetal Medicine Program at McMaster.  In addition, prior to Medical education he completed BSc and MSc degrees in the field of Toxicology at the University of Guelph.  Dr. De France joined the Division of Maternal Fetal Medicine at McMaster in 2001 and has been an active fulltime member since that time.  He has pursued additional training in Clinical Epidemiology while on staff at McMaster University and is currently involved in Clinical, Educational and Research activities.

Dr. Bryon F. De France, BSc, MD, MSc, FRCS(C)

Chief Obstetrics and Gynecology,
Division Head Maternal Fetal Medicine,
Hamilton Health Sciences
Associate Professor, Department of Obstetrics and Gynecology &
Department of Diagnostic Imaging
McMaster University
1200 Main Street West, Room 4D10
Hamilton, ON L8N 3Z5
Mailing Address: 1280 Main Street West
Hamilton, ON L8S 4K1
Tel: (905) 521-2100, Ext. 76253
Fax: (905) 527-2675

Administrative Assistant : Holly Lo Manto



Clinical Interests:

  • Maternal and Fetal Medicine
  • Prenatal Diagnosis
  • Fetal Ultrasound

Research Interests

Areas of Active Research:

  • Clinical Trials
  • Diabetes in Pregnancy
  • Fetal growth and Development

Clinical Trials:

Folic Acid Clinical Trial (FACT) – Local Qualified Investigator
International, Multi-Centered, RCT
The hypothesis of the study is: high dose (4.0 mg per day) supplementation for pregnant women at high risk of developing preeclampsia starting in early pregnancy and continued throughout the entire pregnancy will lower the incidence of preeclampsia.

The trial completed recruitment in November 2015 and the local contribution to recruitment of 161 participants to the final goal of 2464 was 2nd of 72 centers worldwide.

Ongoing Collaborative Work

Dr. Christoph Fusch
Dual closed-loop ex-vivo placenta perfusion

Dr Christoph Fusch, Dr Nina Stein, Dr, Mike Noseworthy
Fetal Body Composition


To view publications, click here

Recent Resident Research

Sandra Gregorovich
“Corticosteroids Compared to Intravenous Immune Globulin for the Treatment of Immune Thrombocytopenia in Pregnancy”

Esther Chin
“Necrotizing Fasciitis in Obstetrics and Gynecology – a systematic review”

Elissa Tepperman – R.T. Weaver Best Research Recipient
Redefining Hadlock Curves for the Diabetic Population

Karen MacMillan
Relative fetal acidemia in pregestational diabetics compared to non-diabetic controls.

Meredith Giffin – R.T. Weaver Best Research Recipient
“Estimating Fetal Birth Weight in Pregestational Diabetics Using the Gestation-Adjusted Projection Method:  Accuracy and Optimal Timing of Estimation

Kersti Ranken – R.T. Weaver Best Research Recipient
Estimation of Fetal Weight in Pregestational Diabetics: A Comparison of 15 Formulas


  • BSc - University of Guelph
  • MSc - University of Guelph
  • MD - McMaster University
  • FRCSC - McMaster

© 201​6 McMaster University  |  1280 Main Street West  |  Hamilton, Ontario ​L8S 4K1  |  905-521-2100   |  Contact Us | Terms of Use & Privacy Policy